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How to pay less for Xtandi

Generic name: enzalutamideUsed for: Prostate cancerMade by Astellas and PfizerNo generic yetLast checked October 1, 2026
Quick answer

There’s no generic yet. Start with the Astellas and Pfizer programs below, matched to how you pay.

Your options, by how you pay

If you haveStart here
No insuranceApply to Medicine Assistance Tool (search this drug). Free drug if you meet income limits. Also compare the maker’s cash price and TrumpRx.gov.
Job or marketplace planA copay card from the official Xtandi website can cut your copay. If your plan denies it, Medicine Assistance Tool (search this drug) may still help.
MedicarePart D costs stop at $2,100 for 2026. Extra Help cuts copays if your income is limited. Charity foundations can help too. Medicare’s negotiated price for Xtandi starts January 1, 2027. Copay cards can’t be used with Medicare.
MedicaidUsually covered for a small copay or none. If it’s denied, your doctor can request prior authorization or suggest a covered alternative.

Find the maker’s program

Xtandi is made by Astellas and Pfizer. Search the drug name in the Medicine Assistance Tool to see its free-drug and savings programs.

Search programs

What to gather before you apply

  • Your prescription, or your doctor’s contact details
  • Proof of income: last year’s tax return or recent pay stubs
  • Your insurance card, or a denial letter if coverage was refused
  • Photo ID and proof of U.S. residency

Need your doctor’s help or appealing a denial? Use our free letter templates.

Common questions

Is there a generic for Xtandi?

Not as of October 2026. Xtandi (enzalutamide) is sold only as a brand-name drug, so the maker’s programs are the main way to lower its cost.

How can I get Xtandi for free or at a lower cost?

Xtandi is made by Astellas and Pfizer. Search the Medicine Assistance Tool for its free-drug and savings programs. With private insurance, check the official Xtandi website for a copay card.

Does Medicare cover Xtandi?

Coverage depends on your Part D plan’s drug list, so check it or use Medicare’s Plan Finder. Part D costs stop at $2,100 for 2026. Extra Help cuts copays if your income is limited. Charity foundations can help too. Medicare’s negotiated price for Xtandi starts January 1, 2027. Copay cards can’t be used with Medicare.

Prices and program rules change. Check the official source before you apply. This page explains cost options only and is not medical advice.