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How to pay less for Epclusa

Generic name: sofosbuvir and velpatasvirUsed for: Hepatitis CMade by GileadGeneric availableLast checked October 1, 2026
Quick answer

A generic (sofosbuvir and velpatasvir) is available and usually costs far less. Ask your pharmacist about switching, then compare cash prices.

Asegua, a Gilead company, sells an authorized generic of Epclusa at a lower list price. Hepatitis C is curable, so ask about it if cost has held you back.

Your options, by how you pay

If you haveStart here
No insuranceCompare generic cash prices at Cost Plus Drugs, TrumpRx.gov and a free discount card.
Job or marketplace planThe generic usually has the lowest copay. A discount card may beat your copay too.
MedicarePart D costs stop at $2,100 for 2026. Extra Help cuts copays if your income is limited. Charity foundations can help too. Copay cards can’t be used with Medicare.
MedicaidUsually covered for a small copay or none. If it’s denied, your doctor can request prior authorization or suggest a covered alternative.

The maker’s assistance program

Gilead Advancing Access helps people who can’t afford Gilead medications. Eligibility depends on income and coverage, and your doctor usually signs part of the application.

Go to Gilead Advancing Access

What to gather before you apply

  • Your prescription, or your doctor’s contact details
  • Proof of income: last year’s tax return or recent pay stubs
  • Your insurance card, or a denial letter if coverage was refused
  • Photo ID and proof of U.S. residency

Need your doctor’s help or appealing a denial? Use our free letter templates.

Common questions

Is there a generic for Epclusa?

Yes. A generic version (sofosbuvir and velpatasvir) is available and usually costs much less than Epclusa. Ask your pharmacist or doctor about switching.

How can I get Epclusa for free or at a lower cost?

Gilead Advancing Access may provide it free if you meet income limits; your doctor signs part of the application. With private insurance, a copay card from the official Epclusa website can lower your copay.

Does Medicare cover Epclusa?

Coverage depends on your Part D plan’s drug list, so check it or use Medicare’s Plan Finder. Part D costs stop at $2,100 for 2026. Extra Help cuts copays if your income is limited. Charity foundations can help too. Copay cards can’t be used with Medicare.

Prices and program rules change. Check the official source before you apply. This page explains cost options only and is not medical advice.